Two studies came out earlier this week in JAMA Internal Medicine stating that there is a potential link between cannabis legalization and a decrease in the amount of prescriptions for opioids (1,2). The first study by Bradford and colleagues concluded that medical cannabis laws were associated with significant reductions in opioid prescriptions for patients in the Medicare Part D population. “This finding was particularly strong in states that permit dispensaries, and for reductions in hydrocodone and morphine prescriptions,” the authors stated.
According to the study (1), this longitudinal analysis of Medicare Part D found that prescriptions filled for all opioids decreased by 2.11 million daily doses/year from an average of 23.08 million daily doses/year when a state instituted any medical cannabis law. Prescriptions for all opioids decreased by 3.742 million daily doses/year when medical cannabis dispensaries opened.
The second paper by Wen and Hockenberry was a population-based, cross-sectional study based on the all-capture Medicaid prescription data from 2011 to 2016. The authors compared the Medicaid prescription data to the medical marijuana and adult-use marijuana laws that were passed during the same time frame to discover if those laws were associated with lower opioid prescribing rates. According to the study, the state implementation of medical marijuana laws was associated with a 5.88% lower rate of opioid prescriptions and the implementation of adult-use marijuana laws was associated with a 6.38% lower rate of opioid prescriptions.
“These findings suggest that medical and adult-use marijuana laws have the potential to reduce opioid prescribing for Medicaid enrollees, a segment of population with disproportionately high risk for chronic pain, opioid use disorder, and opioid overdose,” said the authors (2).
Both of these studies strongly indicate that cannabis can help fight the opioid epidemic. For more information on these studies, please see the full articles at the links provided below.
Ep 25: Cannabis Quality Differentiation Beyond Cannabinoid Content
February 28th 2025In this latest installment of Noid Knowledge we are joined by Julie Kowalski, a leading mind in analytical chemistry and cannabis testing. Julie has arranged a very compelling symposium for Pittcon entitled Cannabis Aroma: Advances and Challenges in Determining and Commercializing Cannabis Product Quality Attributes. It is taking place on Wednesday, March 5, 2025, starting at 9:30 AM in room 209. The session features top notch speakers, including several previous guests of this show, and yours truly, discussing the next generation of quality assessment in cannabis.
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December 26th 2024In the final part of this episode, Evan Friedmann and Yasha Kahn discuss the need for a national entity to centralize cannabis data collection, moving from snapshot data to continuous updates. They emphasize the importance of accurate lab data and adverse event tracking, suggesting QR codes on packaging to report issues. Yasha suggests harsher consequences for result manipulation and suggests collaboration between state departments and federal entities to support underfunded regulators. They also discuss the potential benefits of off-the-shelf testing and the importance of stability testing. Finally, Yasha shares his top three reading recommendations for the audience.