Technobis Crystallization Systems

By utilizing the Crystalline device coupled with a Tornado Raman spectrometer, it is possible to monitor and track polymorphism and morphology at low working volumes.

Automating your solid-state screening process enables you to perform the crystallization experiments with just a small amount of effort. Both CrystalBreeder and Crystal16 are the perfect tools for determining solubility in an easy and efficient manner. The solubility of your compound in organic solvents or water plays an important role when designing a crystallization screen. Knowing the solubility will allow you to select suitable solvents for the different crystallization methods.

The Crystal16 is a powerful system used for diverse solid state screening including co-crystal formation. Using 16 parallel reactors, you can test a wide diversity of crystallization conditions.

The term pharmaceutical salt is used to refer to an ionizable drug that has been combined with a counter-ion to form a neutral complex. More than half of all drug molecules on the market are salts. The main reason behind this is that in general, salts have more desirable aqueous solubility (and implicitly bioavailability) profiles compared to the free acid or the free base API (Active Pharmaceutical Ingredient).