A study published in January 2023 examined the effects of high and low doses of cannabigerol (CBG) on mice liver.
Cannabigerol (CBG) may have therapeutic potential when treating nonalcoholic fatty liver disease (NAFLD), concluded a study published by researchers at the Universities of Utah and Northern Colorado (1). The study, published in MDPI in the Special Issue "Liver Disease, Lifestyle and Cardiovascular Risk,” analyzed the effects of CBG on hepatic steatosis, fibrosis, and inflammation connected to NAFLD (1). Scientists analyzed the livers of mice after being separated into groups, fed specific diets, then given either low or high doses of CBG.
“Overall, our results suggest that the low dose of CBG treatment has a higher potential for alleviating liver damage due to methionine/choline-deficient (MCD)-induced non-alcoholic steatohepatitis (NASH) symptoms, compared to high dose of CBG, which caused elevated liver damage,” read part of the study’s results section (2). “In conclusion, this study provides initial findings and a foundation for future studies on the efficacy of CBG on NASH.”
CBG is called “The Mother Cannabinoid” because all other cannabinoids derive from it. CBG also has potential anti-inflammatory effects similar to other cannabinoids and is non-psychotropic (1,2).
References
Ep 24, Part I: Data Transparency in Cannabis Testing with Yasha Khan
November 21st 2024Evan Friedmann interviews Yasha Khan, co-founder of MCR Labs, about his journey into the cannabis industry and his efforts to promote transparency and integrity in laboratory practices. Yasha discusses the origins of MCR Labs, which began in Massachusetts to meet the needs of the soon-to-be legal medical cannabis market. He explains the challenges faced, including result manipulation by labs and the impact on public health. Yasha's Freedom of Information Act (FOIA) project aimed to gather testing data from 37 states, revealed significant discrepancies in potency and mold results. Despite some states' reluctance to share data, Yasha has made much of this data public, leading to collaborative research and publications on various aspects of cannabis testing.
Assessing Cannabis as a Harm Reduction Strategy: Insights from a Large-Scale Study
November 19th 2024A New Zealand study aimed to assess cannabis use as a harm reduction tool. Findings highlight lifestyle factors, and suggest cannabis-focused harm reduction strategies in reducing other substance use such as alcohol.
Ep 23, Part III: Accreditation in the Cannabis Industry with Susan Audino
October 24th 2024In Part III of this episode, host Evan Friedmann is joined by Susan Audino, PhD, founder of S.A. Audino & Associates, LLC, and co-founder of Saturn Scientific, LLC, to examine the complexities of sampling in the cannabis industry, emphasizing the need for proper sampling plans, and methods.